At Princeton!

Replogle JM, Xu A, Norman TM, Meer EJ, Terry JM, Riordan D, Srinivas N, Mikkelsen TS, Weissman JS, & Adamson B. Direct capture of CRISPR guides enables scalable, multiplexed, and multi-omic Perturb-seq. bioRxiv https://doi.org/10.1101/503367 (2018).

 

2013-2018

Chan M, Smith ZD, Grosswendt S, Kretzmer H, Norman T, Adamson B, Jost M, Quinn JJ, Yang D, A Meissner, & Weissman JS. Molecular recording of mammalian embryogenesisbioRxiv (2018).

Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, & Gilbert LA. Mapping the genetic landscape of human cellsCell 174, 953-967 (2018).

Adamson B, Norman TM, Jost M, & Weissman JS. Approaches to maximize sgRNA-barcode coupling in Perturb-seq screens. bioRxiv  (2018).

Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, & Weissman JS. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell 167, 1867-1822 (2016). 

Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, & Regev A. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic ScreensCell 167, 1853-1866 (2016).

Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, & Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activationeLife 5 (2016).

Izhar L, Adamson B, Ciccia A, Lewis J, Pontano-Vaites L, Leng Y, Liang AC, Westbrook T, Harper JW, & Elledge SJ. A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factorsCell Rep 11, 1486-1500 (2015).

Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, & Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and ActivationCell 159, 647-661 (2014).

 

2010-2013

Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, & Elledge SJ. Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress. Mol Cell 47, 396-409 (2012).

Adamson B, Smogorzewska A, Sigoillot FD, King RW, & Elledge SJ. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage responseNat Cell Biol 14, 318-328 (2012).

Sigoillot FD, Lyman S, Huckins JF, Adamson B, Chung E, Quattrochi B, & King RW. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nat Methods 9, 363-366 (2012).

O’Connell BC, Adamson B, Lydeard JR, Sowa ME, Ciccia A, Bredemeyer AL, Schlabach M, Gygi SP, Elledge SJ, & Harper JW. A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability. Mol Cell 40, 645-657 (2010).

Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiácovo MP, & Elledge SJ. A chromatin localization screen reveals poly(ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damageProc Natl Acad Sci USA 107, 18475-18480 (2010).